ezmtt

ezmtt is a package for analyzing MTT assay data - namely, fitting and plotting curves and calculating IC%.

It mainly serves as a ‘companion package’ for the protocol here, but is flexible enough to support a variety of plate layouts.

Installation

You can install the development version of ezmtt from GitHub with:

# install.packages("devtools")
devtools::install_github("KaiAragaki/ezmtt")

Example

library(ezmtt)

mtt |>
  mtt_fit(
    conditions = list(
      drug_a = c(0, 1, 10, 100, 1000, 10000),
      drug_b = c(0, 1, 10, 100, 1000, 10000),
      NA,
      NA
    ),
    model = c("ll", "lm")
  ) |>
  mtt_plot(ic_pct = 50)
#> Lowest dose is 0, converting to 1e-04
#> Lowest dose is 0, converting to 1e-04